Mesothelioma Stage Information

Patients with stage I disease have a significantly better prognosis than those with more advanced stages. However, because of the relative rarity of this disease, exact survival information based upon stage is limited.[1] A proposed staging system based upon thoracic surgery principles and clinical data is shown below.[2] It is a modification of the older […]

Recurrent Malignant Mesothelioma

Treatment of recurrent mesothelioma usually utilizes procedures and/or agents not previously employed in the initial treatment attempt. No standard treatment approaches have been proven to improve survival or control symptoms for a prolonged period of time. These patients should be considered candidates for phase I and II clinical trials evaluating new biologicals, chemotherapeutic agents, or […]

Localized Malignant Mesothelioma (Stage I)

Standard treatment options:[1] Solitary mesotheliomas: Surgical resection en bloc including contiguous structures to ensure wide disease-free margins. Sessile polypoid lesions should be treated with surgical resection to ensure maximal potential for cure.[2] Intracavitary mesothelioma: Palliative surgery (pleurectomy and decortication) with or without postoperative radiation therapy. Extrapleural pneumonectomy. Palliative radiation therapy. Treatment options under clinical evaluation: […]

Mesothelioma Lawyer & Attorney Rights

Victims of asbestos injuries are entitled to compensation from the manufacturers of asbestos. The amount of compensation varies in each individual case, but it is often a significant amount of money-as much as six or seven figures. This compensation is not a windfall. If you are suffering from an asbestos disease, you are most likely […]

Mesothelioma General Information

Prognosis in this disease is difficult to assess consistently because there is great variability in the time before diagnosis and the rate of disease progression. Various surgical procedures may be possible in selected patients, providing long-term survival without cure. In large retrospective series of pleural mesothelioma patients, important prognostic factors were found to be stage, […]

Cellular Classification

Histologically, these tumors are composed of fibrous or epithelial elements or both. The epithelial form occasionally causes confusion with peripheral anaplastic lung carcinomas or metastatic carcinomas. Attempts at diagnosis by cytology or needle biopsy of the pleura are often unsuccessful. It can be especially difficult to differentiate mesothelioma from adenocarcinoma on small tissue specimens. Thoracoscopy […]

Advanced Malignant Mesothelioma (Stages II, III, and IV)

Standard treatment options: Symptomatic treatment to include drainage of effusions, chest tube pleurodesis, or thoracoscopic pleurodesis.[1] Palliative surgical resection in selected patients.[2,3] Palliative radiation therapy.[4,5] Single-agent chemotherapy. Partial responses have been reported with doxorubicin,epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin, and ifosfamide.[6—8] Combination chemotherapy (under clinical evaluation).[6,7] Information about ongoing clinical trials is available from the NCI Web […]

Malignant Mesothelioma for Health Professionals

Important: This information is intended mainly for use by doctors and other health care professionals. If you have questions about this topic, you can ask your doctor, or call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). # # # Sources of National Cancer Institute Information

Mesothelioma Updates

Researchers with the largest Phase III trial to date for mesothelioma, an aggressive cancer affecting the lining of the lung, reported results showing that patients on a new chemotherapy drug regimen live longer and have less pain than those on an older drug. The findings were announced at the annual meeting of the American Society […]

Questions and Answers About Metastatic Cancer

What is cancer? Cancer is a group of many related diseases that begin in cells, the body’s basic unit of life. The body is made up of many types of cells. Normally, cells grow and divide to produce more cells only when the body needs them. This orderly process helps keep the body healthy. Sometimes […]